25 Series B Healthcare investors
As of October 16, 2026, DryPowder lists 25 Series B Healthcare venture funds. Their median published check range is $500K–$5M (11 of 25 funds publish one). 1 has filed an SEC Form D in the last 90 days: Tribe Capital (Oct 7, 2026).
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- funds listed
- 25
- median check (11 of 25 publish one)
- $500K–$5M
- filed an SEC Form D in the last 90 days
- 1
- last updated, 2026
- Oct 16
Filed a Form D in the last 90 days
- Tribe CapitalPalo Alto$40M offeringFORM D
All 25 Series B Healthcare funds
- Tribe CapitalPalo Alto
Data-driven, systematic approach to partnering with the world's most promising companies. AI and data science engine for underwriting enables…
5 partners listed - Caffeinated CapitalSan Francisco$500K–$5MSeedSeries ASeries BSeries C
Caffeinated offers founders pursuing their life's work an alternative to the hype cycle through long-term thinking, supporting category-defining…
2 partners listed - $250K–$5MSeedSeries ASeries B
Investing in a future where people of color experience true agency and participation in the American economy through supporting entrepreneurs from…
1 partner listed - SignalFireSan Francisco$500K–$5MSeedSeries ASeries B
SignalFire is a VC firm built like a tech company that combines AI tools, data infrastructure, and deep sector expertise with portfolio support to…
Partners not yet listed - Costanoa VenturesSan Francisco$1M–$5MSeries B
Back a select few founders solving big, hard problems with long-term partnership support, leveraging decades of operational expertise and consistent…
2 partners listed - GreycroftNew York$500K–$5MSeedSeries ASeries BSeries CGrowth
Partner with brilliant founders to bring things of real wonder into the world by backing innovative companies that upend the status quo across…
Partners not yet listed - $25K–$2MSeedPre-SeedSeries ASeries BGrowth
To give investors access to the best possible venture deals. We partner with lead VCs, apply rigorous diligence, and make investing straightforward.
Partners not yet listed - SeedSeries ASeries B
Calibrate partners with elite technical founders to turn deep tech breakthroughs (AI, computer vision, autonomy, robotics) into scalable commercial…
2 partners listed - $1M–$100MSeedSeries ASeries BGrowth
Invests in companies using technology to solve important problems in healthcare, artificial intelligence, cybersecurity, agriculture, transportation,…
17 partners listed - Correlation VenturesSan FranciscoSeedSeries ASeries B
Correlation Ventures backs groundbreaking technology and data science companies that solve industry problems through rapid decision-making and…
Partners not yet listed - SeedPre-SeedSeries ASeries BSeries C
We help founders build a healthier & more sustainable future by investing capital, time & belief to accelerate success. We invest in driven founders…
Partners not yet listed - SeedSeries ASeries BGrowth
Back the unique, the mavericks, and the outliers at the earliest stages in Europe. Invest in the best ideas and brightest minds leveraging…
Partners not yet listed - SeedSeries ASeries B
Invest in teams building AI and intelligent machines that unlock human potential by transforming foundational industries. AI and robotics will allow…
Partners not yet listed - $1M–$15MSeedSeries ASeries B
Investing in exceptional founders transforming healthcare by rebuilding healthcare's operating system with software, data, and AI. Focus on…
Partners not yet listed - $5M–$25MSeries ASeries B
We work with founders driving structural change in two complex systems: healthcare and financial services. With unparalleled networks and decades of…
6 partners listed - DaphniParisSeedSeries ASeries BGrowth
Daphni backs visionary entrepreneurs with deep conviction, supporting startups where vision meets conviction across diverse sectors.
Partners not yet listed - Series ASeries BSeries C
Help support entrepreneurs building globally ambitious companies that matter. Focus on companies solving meaningful problems across diverse sectors…
Partners not yet listed - SeedSeries ASeries B
Early-stage tech investments in the US and Israel, providing access and meaningful connections to help brilliant minds breakthrough.
Partners not yet listed - Peterson VenturesUnknownSeedSeries ASeries B
Help great people build great businesses starting at seed stage, backing big ideas and swinging for the fences.
Partners not yet listed - SeedSeries ASeries B
Building next-generation companies to enhance healthy lifespan by investing in transformative healthcare companies targeting age-related diseases and…
Partners not yet listed - SeedSeries ASeries BSeries CGrowth
Multi-stage venture capital firm that goes beyond traditional VC playbook by providing entrepreneurs support of a global ecosystem, connecting…
Partners not yet listed - SeedSeries ASeries BGrowth
Long-term partners to audacious entrepreneurs, creating and investing alongside them to develop tomorrow's leaders. Conviction-driven approach guided…
Partners not yet listed - SeedSeries ASeries B
Back deep-tech founders who pair technical ambition with decisive execution, providing value beyond capital through hands-on partnership and…
Partners not yet listed - SeedSeries BGrowth
Partner with mission-driven entrepreneurs to build transformative life sciences companies focused on developing and commercializing impactful…
Partners not yet listed - $250K–$10MSeedSeries ASeries B
Our mission is to identify and support companies that live at the intersection of for-profit & for-good
Partners not yet listed
How this list is built
DryPowder lists every fund with a public profile tagged Series B and Healthcare. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 11 funds that publish one.
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Frequently asked questions
How many Series B Healthcare VCs are there?
As of October 16, 2026, DryPowder lists 25 Series B Healthcare venture funds with a public profile. The first 5 on this page are Tribe Capital, Caffeinated Capital, Impact America Fund, SignalFire and Costanoa Ventures.
Which Series B Healthcare VCs are actively investing right now?
1 of the 25 filed a verified SEC Form D in the last 90 days, a sign of a new fund being raised: Tribe Capital (Oct 7, 2026). Each filing links to its record on SEC EDGAR.
What check size do Series B Healthcare VCs write?
The median published range is $500K–$5M, across the 11 of 25 funds that publish a check size. Published checks on this list run from $25K to $100M.
Where are Series B Healthcare VCs based?
Of the 25 Series B Healthcare venture funds, 4 are in San Francisco, 1 is in New York, 1 is in Palo Alto and 1 is in Paris. The rest are elsewhere or have no headquarters city on file.
How does DryPowder build this list?
A fund is listed when its public profile is tagged Series B and Healthcare. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of October 16, 2026.
Sources
- SEC EDGAR: Form D, Tribe Capital ($40M offering), filed
- Website: Tribe Capital website
- Website: Caffeinated Capital website
- Website: Impact America Fund website
- Website: SignalFire website
- Website: Costanoa Ventures website
- Website: Greycroft website
- Website: Alumni Ventures website
- Website: Calibrate Ventures website
- Method: How DryPowder builds its data
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