DryPowder

26 Series B Healthcare Investors — 21 Currently Deploying

Updated

26
Total funds
21
Currently deploying
81%
Deployment rate
$25K–$100M
Typical check range

Funds (26)

Caffeinated Capital
● Deploying$500K–$5MSan Francisco

Caffeinated offers founders pursuing their life's work an alternative to the hype cycle through long-term thinking, supporting category-defining companies across all sectors that w

Calibrate Ventures
● Deploying

Calibrate partners with elite technical founders to turn deep tech breakthroughs (AI, computer vision, autonomy, robotics) into scalable commercial advantages across transportation

Impact America Fund
● Deploying$250K–$5M

Investing in a future where people of color experience true agency and participation in the American economy through supporting entrepreneurs from overlooked communities.

SignalFire
● Deploying$500K–$5MSan Francisco

SignalFire is a VC firm built like a tech company that combines AI tools, data infrastructure, and deep sector expertise with portfolio support to help founders scale faster. The f

Tribe Capital
● Deploying$500K–$5MPalo Alto

Data-driven, systematic approach to partnering with the world's most promising companies. AI and data science engine for underwriting enables quantitative decision-making across ve

Greycroft
● Deploying$500K–$5MNew York

Partner with brilliant founders to bring things of real wonder into the world by backing innovative companies that upend the status quo across software, sustainability, and consume

Costanoa Ventures
● Deploying$1M–$5MSan Francisco

Back a select few founders solving big, hard problems with long-term partnership support, leveraging decades of operational expertise and consistent success to help founders reach

GV
$1M–$100M

Invests in companies using technology to solve important problems in healthcare, artificial intelligence, cybersecurity, agriculture, transportation, and other sectors

Correlation Ventures
● DeployingSan Francisco

Correlation Ventures backs groundbreaking technology and data science companies that solve industry problems through rapid decision-making and industry-leading networks.

Comet Labs
● Deploying

Invest in teams building AI and intelligent machines that unlock human potential by transforming foundational industries. AI and robotics will allow humanity to rethink and rebuild

Flare Capital Partners
● Deploying$1M–$15M

Investing in exceptional founders transforming healthcare by rebuilding healthcare's operating system with software, data, and AI. Focus on technology infrastructure across the $5.

Wireframe Ventures
● Deploying

We help founders build a healthier & more sustainable future by investing capital, time & belief to accelerate success. We invest in driven founders building pioneering companies t

btov Partners
● Deploying

Back the unique, the mavericks, and the outliers at the earliest stages in Europe. Invest in the best ideas and brightest minds leveraging generations of experience and Europe's st

Oak HC/FT
$5M–$25M

We work with founders driving structural change in two complex systems: healthcare and financial services. With unparalleled networks and decades of sector experience.

Mindset Ventures
● Deploying

Early-stage tech investments in the US and Israel, providing access and meaningful connections to help brilliant minds breakthrough.

Cathay Innovation
● Deploying

Multi-stage venture capital firm that goes beyond traditional VC playbook by providing entrepreneurs support of a global ecosystem, connecting innovators everywhere.

Daphni
● DeployingParis

Daphni backs visionary entrepreneurs with deep conviction, supporting startups where vision meets conviction across diverse sectors.

Peterson Ventures
● DeployingUnknown

Help great people build great businesses starting at seed stage, backing big ideas and swinging for the fences.

Amplo
● Deploying

Help support entrepreneurs building globally ambitious companies that matter. Focus on companies solving meaningful problems across diverse sectors and geographies.

Apollo Projects
● Deploying

Building next-generation companies to enhance healthy lifespan by investing in transformative healthcare companies targeting age-related diseases and aging itself through biotechno

Otium Capital
● Deploying

Long-term partners to audacious entrepreneurs, creating and investing alongside them to develop tomorrow's leaders. Conviction-driven approach guided by values of individual focus,

Acme Capital
● Deploying

Back deep-tech founders who pair technical ambition with decisive execution, providing value beyond capital through hands-on partnership and conviction-driven investing.

Lumira Ventures Seed
● Deploying

Partner with mission-driven entrepreneurs to build transformative life sciences companies focused on developing and commercializing impactful products for patients.

Sequoia Capital

Partner with bold founders to build legendary companies across technology sectors

Alumni Ventures
$25K–$2M

To give investors access to the best possible venture deals. We partner with lead VCs, apply rigorous diligence, and make investing straightforward.

Collaborative Fund
$250K–$10M

Our mission is to identify and support companies that live at the intersection of for-profit & for-good

Which of these Series B Healthcare funds actually fits your startup?

DryPowder's AI matching ranks all 26 by thesis fit, check size, and deployment status.

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Frequently asked questions

How many series b healthcare investors are actively deploying right now?

DryPowder tracks 26 series b healthcare funds. Of these, 21 are currently deploying capital based on recent fund closes, portfolio activity, and partner signals. Use DryPowder's fund matching to see which ones fit your specific startup.

What check size do series b healthcare VCs write?

Among 26 series b healthcare funds on DryPowder, check sizes run from $25K–$100M. Ranges vary by fund size, vintage, and whether the fund leads rounds. Each fund profile shows check size detail and lead preference.

How do I get a meeting with a series b healthcare VC?

A warm intro is still the fastest path. Most series b healthcare VCs on DryPowder do accept cold outreach or direct applications, but response rates vary widely by fund. Before reaching out, use DryPowder's AI matching to get a fit score and specific talking points. Founders who lead with thesis-aligned framing get significantly better response rates than those sending the same deck to every fund on a list.

How long does a Series B process take, and how is it different from Series A?

Series B processes typically run 3-6 months and are significantly more diligence-intensive than Series A. Investors will conduct deep cohort analysis, churn reviews, and GTM efficiency audits. Most Series B investors want to lead or co-lead, so you are running a smaller, more targeted process than at earlier stages. Financial modeling and competitive positioning matter as much as the founding narrative at this point.

How many series b healthcare investors should I be talking to at once?

Most fundraisers recommend a parallel process: identify 20-40 target investors but approach your highest-fit funds first. Of the 21 series b healthcare funds currently deploying, not all will match your specific stage and sector. Use fund matching to find your top 10-15, approach those first, collect feedback, then go wider. Going to every fund simultaneously without qualifying first burns bridges and dilutes the urgency that helps close a round.

How is DryPowder different from building a VC list on LinkedIn or Crunchbase?

The fund list you build on LinkedIn or Crunchbase is roughly the same list every other founder is building. DryPowder adds three things a manual search cannot: deployment signals (which funds have recently closed new vehicles and are actively writing checks), AI thesis matching (which of the 26 series b healthcare funds actually fits your specific startup, ranked by fit), and verified partner contact details. The goal is 15 targeted, thesis-aligned pitches instead of 150 generic ones.

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