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4 Series B Healthcare investors in San Francisco

As of October 16, 2026, DryPowder lists 4 Series B Healthcare venture funds in San Francisco. Their median published check range is $500K–$5M (3 of 4 funds publish one). None has filed a verified SEC Form D in the last 90 days.

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Which Series B Healthcare funds in San Francisco are writing checks right now?

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funds listed
4
median check (3 of 4 publish one)
$500K–$5M
filed an SEC Form D in the last 90 days
0
last updated, 2026
Oct 16

All 4 Series B Healthcare funds in San Francisco

  1. Caffeinated Capital
    $500K–$5MSeedSeries ASeries BSeries C

    Caffeinated offers founders pursuing their life's work an alternative to the hype cycle through long-term thinking, supporting category-defining…

    2 partners listed
  2. SignalFire
    $500K–$5MSeedSeries ASeries B

    SignalFire is a VC firm built like a tech company that combines AI tools, data infrastructure, and deep sector expertise with portfolio support to…

    Partners not yet listed
  3. Costanoa Ventures
    $1M–$5MSeries B

    Back a select few founders solving big, hard problems with long-term partnership support, leveraging decades of operational expertise and consistent…

    2 partners listed
  4. Correlation Ventures
    SeedSeries ASeries B

    Correlation Ventures backs groundbreaking technology and data science companies that solve industry problems through rapid decision-making and…

    Partners not yet listed

How this list is built

DryPowder lists every fund with a public profile tagged Series B and Healthcare and headquartered in San Francisco. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 3 funds that publish one.

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Frequently asked questions

How many Series B Healthcare VCs in San Francisco are there?

As of October 16, 2026, DryPowder lists 4 Series B Healthcare venture funds in San Francisco with a public profile. The first 4 on this page are Caffeinated Capital, SignalFire, Costanoa Ventures and Correlation Ventures.

Which Series B Healthcare VCs in San Francisco are actively investing right now?

None of the 4 filed a verified SEC Form D in the last 90 days. A Form D is filed when a fund starts raising; SPVs and single-deal vehicles are not counted.

What check size do Series B Healthcare VCs in San Francisco write?

The median published range is $500K–$5M, across the 3 of 4 funds that publish a check size. Published checks on this list run from $500K to $5M.

How does DryPowder build this list?

A fund is listed when its public profile is tagged Series B and Healthcare and its headquarters is San Francisco. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of October 16, 2026.

Sources

Updated