Wireframe Ventures
Pre-Seed to Series D venture capital firm
Wireframe Ventures is a Pre-Seed to Series D venture capital firm that invests in Bioscience, Climate Tech and Energy. DryPowder has no SEC Form D on file for Wireframe Ventures as of June 3, 2026. Partners at Wireframe Ventures include Harsh Patel (Co-founder) and Paul Straub (Co-founder).
Updated · Sources: fund website
- Stages
- Pre-Seed–Series D
Overview
Wireframe Ventures at a glance
- Stage
- Pre-Seed, Seed, Series A, Series B, Series C, Series D
- Sectors
- Bioscience, Climate Tech, Energy, Healthcare, Transportation, AI, Enterprise Software
- Cold inbound
- Accepted
- Website
- wireframevc.com
Investment thesis
We help founders build a healthier & more sustainable future by investing capital, time & belief to accelerate success. We invest in driven founders building pioneering companies that improve our world across five domains: biology, climate, AI/automation, healthcare, and zero-carbon transportation.
Stated on wireframevc.comWEBSITE
What sets Wireframe Ventures apart
- Hands-on founder support from day-one with whiteboarding and strategic advising
- Long-term partnership model with multi-round follow-on support
- Deep domain expertise in climate tech, biotech, and energy sectors
- Portfolio includes multiple unicorns and major exits (Palantir, Enveda)
Recent investments
DryPowder has tracked these recent investments from Wireframe Ventures: Caladan Bio (February 2024), Great Sky (March 2026) and Cocoon (March 2026).
What the portfolio shows
Portfolio 20
Backed: Mammoth Biosciences, Tyba, SPAN.io + 17 more
Partners
2 partners at Wireframe Ventures
- Harsh Patel
Co-founder
- Paul Straub
Co-founder
From the fund's website. Contact details not yet verified.
Similar funds
Funds like Wireframe Ventures
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HAXEnergy, Advanced Manufacturing · $550K
Crosscut VenturesClimate Tech, Space Tech · $250K–$2M
Investor lists that include Wireframe Ventures
FAQ
Questions about Wireframe Ventures
What does Wireframe Ventures invest in?
Wireframe Ventures is a Seed, Pre-Seed, Series A, Series B, Series C, Series D stage Bioscience, Climate tech, Energy, Healthcare, Transportation, AI, Enterprise software investor, primarily investing in US. Their thesis: We help founders build a healthier & more sustainable future by investing capital, time & belief to accelerate success. We invest in driven founders building pioneering companies that improve our world across five domains: biology, climate, AI/automation, healthcare, and zero-carbon transportation.
What makes Wireframe Ventures different from other funds?
Wireframe Ventures stands out on 4 points: Hands-on founder support from day-one with whiteboarding and strategic advising; Long-term partnership model with multi-round follow-on support; Deep domain expertise in climate tech, biotech, and energy sectors; Portfolio includes multiple unicorns and major exits (Palantir, Enveda).
What has Wireframe Ventures invested in recently?
Recent investments DryPowder has tracked from Wireframe Ventures include Caladan Bio (February 2024), Great Sky (March 2026), Cocoon (March 2026).
What other funds are similar to Wireframe Ventures?
Funds with an overlapping stage and sector focus include Caffeinated Capital, Calibrate Ventures, Acme Capital.
How do I reach Wireframe Ventures?
Wireframe Ventures accepts cold inbound, so a warm introduction is not required.
Sources
Updated