18 Series A AI & Machine Learning investors in San Francisco

funds listed

18

median check (13 of 18 publish one)

$500K–$5M

filed an SEC Form D in the last 90 days

0

last updated, 2026

Oct 16

1. 

   Caffeinated Capital
   $500K–$5MSeedSeries ASeries BSeries C

   Caffeinated offers founders pursuing their life's work an alternative to the hype cycle through long-term thinking, supporting category-defining…

   2 partners listedView fund →
2. 

   Operator Collective
   $250K–$2.5MSeedSeries A

   Operator Collective is an early-stage B2B venture firm that connects founders to exceptional enterprise operators, believing companies succeed…

   20 partners listedView fund →
3. 

   True Ventures
   $250K–$2MSeedSeries A

   Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check…

   4 partners listedView fund →
4. 

   BOLDstart Ventures
   $250K–$5MSeedSeries A

   Partner with bold technical founders from inception, before product or first check, backing AI-native infrastructure, security, apps, and models to…

   1 partner listedView fund →
5. 

   Amplify Partners
   $500K–$3MSeedSeries A

   Amplify invests in technical founders building the next generation of applications, models, tools, and infrastructure. For almost 15 years they have…

   2 partners listedView fund →
6. 

   NFX
   $250K–$2MSeedSeries A

   NFX identifies and backs founders building companies with network effects. The fund emphasizes software development, founder support through…

   6 partners listedView fund →
7. 

   Unusual Ventures
   $500K–$4MSeedSeries A

   The product-market fit partner for technical enterprise founders, turning product-market fit from improbable to inevitable through proprietary…

   Partners not yet listedView fund →
8. 

   Kindred Ventures
   $500K–$5MSeedSeries A

   Back visionary and relentless founders building the future using technology and science. Belief in AGI for good, decentralized systems, personalized…

   Partners not yet listedView fund →
9. 

   Pillar VC
   $500K–$5MSeedSeries A

   Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming…

   Partners not yet listedView fund →
10. 

    Zetta Venture Partners
    $500K–$5MSeedSeries A

    First believers in AI Native founders, providing zero to one capital and hands-on support for builders of AI Native applications, infrastructure, and…

    Partners not yet listedView fund →
11. 

    Sequoia Capital
    $500K–$50MSeedSeries ASeries BSeries CGrowth

    Help the daring build legendary companies through capital, expertise, and network.

    18 partners listedView fund →
12. 

    Footwork
    $1M–$15MSeedSeries A

    Lead and co-lead Series A and Seed rounds in companies with early signs of product-market fit, focusing on consumer technology and consumerization of…

    2 partners listedView fund →
13. 

    Storm Ventures
    $500K–$10MSeedSeries ASeries B

    Early stage B2B-focused venture firm specializing in building enterprise leaders through disruptive B2B AI software investments in enterprise…

    7 partners listedView fund →
14. 

    AgFunder
    SeedSeries ASeries B

    Investing in deeptech and foundational technologies that remove structural constraints to sustainable scale in food, agriculture, and planetary…

    Partners not yet listedView fund →
15. 

    Mayfield Fund
    SeedSeries A

    First institutional investor for early-stage AI founders, with 70% of investments beginning at inception. People-first approach to building…

    Partners not yet listedView fund →
16. 

    Maven Ventures
    SeedSeries ASeries B

    Invest in technical founders building software that will improve millions of consumers' lives. Back bold founders with a vision worth fighting for.

    Partners not yet listedView fund →
17. 

    Greylock Partners
    SeedPre-SeedSeries A

    First-check investor (pre-seed, seed, series A) deeply focused on AI-first companies. Partners selectively, cares deeply, and strives for excellence…

    Partners not yet listedView fund →
18. 

    Piva Capital
    SeedSeries ASeries B

    Piva Capital invests in people, companies, and breakthrough technologies at the inflection of scientific breakthrough and mass market impact to usher…

    Partners not yet listedView fund →

DryPowder lists every fund with a public profile tagged Series A and AI & Machine Learning and headquartered in San Francisco. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 13 funds that publish one.