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22 Series A Biotech investors

As of October 16, 2026, DryPowder lists 22 Series A Biotech venture funds. Their median published check range is $250K–$2.5M (7 of 22 funds publish one). 1 has filed an SEC Form D in the last 90 days: Serra Capital (Oct 7, 2026).

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funds listed
22
median check (7 of 22 publish one)
$250K–$2.5M
filed an SEC Form D in the last 90 days
1
last updated, 2026
Oct 16

Filed a Form D in the last 90 days

Each date links to its SEC EDGAR filing

All 22 Series A Biotech funds

  1. True Ventures
    San Francisco
    $250K–$2MSeedSeries A

    Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check…

    4 partners listed
  2. Lewis and Clark Ventures
    $2M–$3MSeries A

    Partner with visionary founders to build iconic B2B software companies. Early stage venture firm managed by former founders and operators investing…

    9 partners listed
  3. NFX
    San Francisco
    $250K–$2MSeedSeries A

    NFX identifies and backs founders building companies with network effects. The fund emphasizes software development, founder support through…

    6 partners listed
  4. BoxGroup
    New York
    $250K–$2.5MSeedSeries A

    Investing in dreams at the earliest stage, backing founders across marketplaces, fintech, developer tools, frontier tech, climate, and experimental…

    Partners not yet listed
  5. Pillar VC
    San Francisco
    $500K–$5MSeedSeries A

    Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming…

    Partners not yet listed
  6. Capital Factory
    Austin
    $25K–$2MSeedSeries A

    Back the most ambitious founders in Texas advancing civilization through deep tech across space, energy, bio, and AI — with cash, customers, and the…

    Partners not yet listed
  7. Speedinvest
    $250K–$3MSeedSeries ASeries BGrowth

    Speedinvest provides European startups with 'more expertise, connections, reach, and momentum' through specialist investment teams across six core…

    Partners not yet listed
  8. Serra Capital
    Champaign
    SeedSeries AFORM D

    Catalyzing innovation through early-stage tech startup funding across the United States, with over 100 companies funded to date.

    4 partners listed
  9. AgFunder
    San Francisco
    SeedSeries ASeries B

    Investing in deeptech and foundational technologies that remove structural constraints to sustainable scale in food, agriculture, and planetary…

    Partners not yet listed
  10. AME Cloud Ventures
    Palo Alto
    SeedSeries ASeries B

    Investing in entrepreneurs building infrastructure and value chains around data, from the full data stack (infrastructure to applications) with…

    Partners not yet listed
  11. Correlation Ventures
    San Francisco
    SeedSeries ASeries B

    Correlation Ventures backs groundbreaking technology and data science companies that solve industry problems through rapid decision-making and…

    Partners not yet listed
  12. CincyTech
    Cincinnati
    SeedSeries A

    Invest in innovative founders tackling the world's complex challenges, partnering early to help transform ideas into world-class companies.

    Partners not yet listed
  13. Golden Ventures
    Toronto
    SeedSeries ASeries B

    Founder-driven investing focused on bold teams and transformative ideas. Hands-on approach informed by past lives as founders and operators.

    Partners not yet listed
  14. Dentsu Ventures
    Tokyo
    SeedSeries ASeries BSeries CGrowth

    Support domestic and international startups through capital provision and business collaboration, leveraging Dentsu Group's creative and strategic…

    Partners not yet listed
  15. Innovation Endeavors
    SeedSeries ASeries B

    Early-stage venture firm investing in technical founders solving hard engineering and science problems through the 'Super Evolution' — a non-linear…

    Partners not yet listed
  16. Cathay Innovation
    SeedSeries ASeries BSeries CGrowth

    Multi-stage venture capital firm that goes beyond traditional VC playbook by providing entrepreneurs support of a global ecosystem, connecting…

    Partners not yet listed
  17. Atlas Venture Seed
    SeedSeries A

    Building breakthrough biotechs through partnerships with world-class life science entrepreneurs, translating groundbreaking science into…

    Partners not yet listed
  18. Mindset Ventures
    SeedSeries ASeries B

    Early-stage tech investments in the US and Israel, providing access and meaningful connections to help brilliant minds breakthrough.

    Partners not yet listed
  19. Hardware Club
    SeedSeries A

    Back founders on a mission to industrialize scientific and technological progress.

    Partners not yet listed
  20. Level Ventures
    New York
    SeedSeries A

    Capital partner to outlier managers and entrepreneurs, building systems for speed, clarity, and conviction in investment decisions.

    Partners not yet listed
  21. Pentech Ventures
    London
    SeedSeries ASeries B

    Supporting ambitious founders to build category defining companies

    Partners not yet listed
  22. Partech
    SeedSeries ASeries BSeries CGrowth
    Partners not yet listed

How this list is built

DryPowder lists every fund with a public profile tagged Series A and Biotech. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 7 funds that publish one.

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Frequently asked questions

How many Series A Biotech VCs are there?

As of October 16, 2026, DryPowder lists 22 Series A Biotech venture funds with a public profile. The first 5 on this page are True Ventures, Lewis and Clark Ventures, NFX, BoxGroup and Pillar VC.

Which Series A Biotech VCs are actively investing right now?

1 of the 22 filed a verified SEC Form D in the last 90 days, a sign of a new fund being raised: Serra Capital (Oct 7, 2026). Each filing links to its record on SEC EDGAR.

What check size do Series A Biotech VCs write?

The median published range is $250K–$2.5M, across the 7 of 22 funds that publish a check size. Published checks on this list run from $25K to $5M.

Where are Series A Biotech VCs based?

Of the 22 Series A Biotech venture funds, 5 are in San Francisco, 2 are in New York, 1 is in London and 1 is in Palo Alto. The rest are elsewhere or have no headquarters city on file.

How does DryPowder build this list?

A fund is listed when its public profile is tagged Series A and Biotech. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of October 16, 2026.

Sources

Updated