DryPowder

12 Seed Biotech Investors in San Francisco — 12 Currently Deploying

Updated

12
Total funds
12
Currently deploying
100%
Deployment rate
$100K–$50M
Typical check range

Funds (12)

Boost VC
● Deploying$500K–$500K

Invest first in founders making mutants a reality by reimagining the universe. Generalist investors backing companies that make 1 billion lives better through bold bets in deep tec

True Ventures
● Deploying$250K–$2M

Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check before others think you're onto

Initialized Capital
● Deploying$250K–$5M

Champion inspired and obsessive builders across seed stage, from enterprise SaaS to sustainability, health, hard tech, AI, infrastructure, consumer, and crypto. Provide guidance fr

Khosla Ventures (Seed)
● Deploying$500K–$50M

Bold, early, impactful ventures with brutal honesty. Believe in world-class teams making contrarian bets on impossibly big ideas, from AI to cleantech to deep tech.

NFX
● Deploying$250K–$2M

NFX identifies and backs founders building companies with network effects. The fund emphasizes software development, founder support through content/tools, and emerging technologie

Inception Studio Capital
● Deploying$100K–$1.5M

Experienced founders (particularly serial/exit founders) win 22x more often. Zero-equity retreats attract elite repeat founders who avoid traditional accelerators, enabling first-m

Pioneer Fund
● Deploying$250K–$2M

A fund of 500+ Y Combinator alumni investing in and supporting top startups from Y Combinator, the world's top accelerator.

AgFunder
● Deploying

Investing in deeptech and foundational technologies that remove structural constraints to sustainable scale in food, agriculture, and planetary health, with AI as core infrastructu

Pillar VC
● Deploying$500K–$5M

Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming world-changing companies, particularly in

Correlation Ventures
● Deploying

Correlation Ventures backs groundbreaking technology and data science companies that solve industry problems through rapid decision-making and industry-leading networks.

Data Collective (DCVC)
● Deploying$1M–$25M

Deep tech venture capital backing brilliant entrepreneurs addressing the hardest, highest-stakes problems in the world, using AI to unlock potential across sectors.

Bessemer Venture Partners (Seed)
● Deploying

Partner with entrepreneurs from early days through every stage of growth, focusing on transformative technology across AI/ML, biotech, cloud, consumer, and crypto sectors.

Which of these Seed Biotech funds actually fits your startup?

DryPowder's AI matching ranks all 12 by thesis fit, check size, and deployment status.

Get my fund matches →

Related investor lists

Seed FintechSeed AI & Machine LearningSeed SaaSSeed HealthcareSeed ConsumerSeed Crypto & Web3

Frequently asked questions

How many seed biotech investors are actively deploying right now?

DryPowder tracks 12 seed biotech funds. Of these, 12 are currently deploying capital based on recent fund closes, portfolio activity, and partner signals. Use DryPowder's fund matching to see which ones fit your specific startup.

What check size do seed biotech VCs write?

Among 12 seed biotech funds on DryPowder, check sizes run from $100K–$50M. Ranges vary by fund size, vintage, and whether the fund leads rounds. Each fund profile shows check size detail and lead preference.

How do I get a meeting with a seed biotech VC?

A warm intro is still the fastest path. Most seed biotech VCs on DryPowder do accept cold outreach or direct applications, but response rates vary widely by fund. Before reaching out, use DryPowder's AI matching to get a fit score and specific talking points. Founders who lead with thesis-aligned framing get significantly better response rates than those sending the same deck to every fund on a list.

How long does a seed round typically take to close?

Seed rounds typically take 3-6 months from first meeting to close. Most of that time is spent on qualification: investors want to see early traction, run multiple meetings, and often complete reference checks. With a committed lead who sets terms, the rest of the round usually fills within 2-4 weeks. Without a lead, the process drags. DryPowder's deployment signals help identify which seed funds are actively writing checks right now versus sitting between vehicles.

How many seed biotech investors should I be talking to at once?

Most fundraisers recommend a parallel process: identify 20-40 target investors but approach your highest-fit funds first. Of the 12 seed biotech funds currently deploying, not all will match your specific stage and sector. Use fund matching to find your top 10-15, approach those first, collect feedback, then go wider. Going to every fund simultaneously without qualifying first burns bridges and dilutes the urgency that helps close a round.

How is DryPowder different from building a VC list on LinkedIn or Crunchbase?

The fund list you build on LinkedIn or Crunchbase is roughly the same list every other founder is building. DryPowder adds three things a manual search cannot: deployment signals (which funds have recently closed new vehicles and are actively writing checks), AI thesis matching (which of the 12 seed biotech funds actually fits your specific startup, ranked by fit), and verified partner contact details. The goal is 15 targeted, thesis-aligned pitches instead of 150 generic ones.

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