13 Pre-Seed Biotech Investors — 11 Currently Deploying

Invest first in founders making mutants a reality by reimagining the universe. Generalist investors backing companies that make 1 billion lives better through bold bets in deep tec…

Thesis-driven early-stage firm backing visionary founders building technologies of the future in Vertical AI, Deep Tech, Health, and Bio with strong data moats and Systems of Recor…

Back European founders with strong qualities (not CV/pedigree) building businesses for a better human future, assessed on characteristics like productivity, grit, and commercial ac…

Petri develops pre-seed companies attacking the world's largest problems at the frontier of biology and engineering, believing the future of biotech is founder-led.

Experienced founders (particularly serial/exit founders) win 22x more often. Zero-equity retreats attract elite repeat founders who avoid traditional accelerators, enabling first-m…

Equitable venture capital model where every founder backed becomes a co-owner of the fund. Early-stage investments in mission-driven, pre-seed and seed founders who are outliers, o…

Pre-Seed and Seed investors partnering with visionary founders. We believe Artificial Intelligence will disrupt every industry.

Backing mission-driven, outlier founders at pre-seed and seed stage across UK, Europe and North America through generalist and institutional thesis-driven funds.

Partner early with founders building enduring companies with conviction before consensus, often being the first check from pre-seed to seed stage.

Partner with exceptional people to help them realize their full potential across pre-seed, seed, growth, and public market stages through long-term founder relationships.

Deep tech and hardware-focused accelerator investing in frontier technologies with global reach

Every founder deserves an equal opportunity to scale their business. We look for great teams who have the ability to capture a compelling market opportunity. We invest in high grow…

Blue Ivy Ventures provides Yale alumni accredited investors access to diversified venture capital investments co-invested alongside leading VC firms, combining a curated annual fun…

How many pre-seed biotech investors are actively deploying right now?

DryPowder tracks 13 pre-seed biotech funds. Of these, 11 are currently deploying capital based on recent fund closes, portfolio activity, and partner signals. Use DryPowder's fund matching to see which ones fit your specific startup.

What check size do pre-seed biotech VCs write?

Among 13 pre-seed biotech funds on DryPowder, check sizes run from $50K–$3M. Ranges vary by fund size, vintage, and whether the fund leads rounds. Each fund profile shows check size detail and lead preference.

How do I get a meeting with a pre-seed biotech VC?

A warm intro is still the fastest path. Most pre-seed biotech VCs on DryPowder do accept cold outreach or direct applications, but response rates vary widely by fund. Before reaching out, use DryPowder's AI matching to get a fit score and specific talking points. Founders who lead with thesis-aligned framing get significantly better response rates than those sending the same deck to every fund on a list.

How long does a pre-seed round take to close?

Most pre-seed rounds close in 4-8 weeks once a lead is committed. The process is faster than seed because checks are smaller and terms are simpler. A SAFE or convertible note is standard. Founders who close quickly typically have a lead committed, 2-3 other investors lined up, and a hard deadline. Open-ended rounds with no timeline tend to stall.

How many pre-seed biotech investors should I be talking to at once?

Most fundraisers recommend a parallel process: identify 20-40 target investors but approach your highest-fit funds first. Of the 11 pre-seed biotech funds currently deploying, not all will match your specific stage and sector. Use fund matching to find your top 10-15, approach those first, collect feedback, then go wider. Going to every fund simultaneously without qualifying first burns bridges and dilutes the urgency that helps close a round.

How is DryPowder different from building a VC list on LinkedIn or Crunchbase?

The fund list you build on LinkedIn or Crunchbase is roughly the same list every other founder is building. DryPowder adds three things a manual search cannot: deployment signals (which funds have recently closed new vehicles and are actively writing checks), AI thesis matching (which of the 13 pre-seed biotech funds actually fits your specific startup, ranked by fit), and verified partner contact details. The goal is 15 targeted, thesis-aligned pitches instead of 150 generic ones.