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8 Series A Infrastructure investors in San Francisco

As of September 21, 2026, DryPowder lists 8 Series A Infrastructure venture funds in San Francisco. Their median published check range is $500K–$5M (6 of 8 funds publish one). None has filed a verified SEC Form D in the last 90 days.

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funds listed
8
median check (6 of 8 publish one)
$500K–$5M
filed an SEC Form D in the last 90 days
0
last updated, 2026
Sep 21

All 8 Series A Infrastructure funds in San Francisco

  1. True Ventures
    $250K–$2MSeedSeries A

    Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check…

    4 partners listed
  2. BOLDstart Ventures
    $250K–$5MSeedSeries A

    Partner with bold technical founders from inception, before product or first check, backing AI-native infrastructure, security, apps, and models to…

    1 partner listed
  3. Amplify Partners
    $500K–$3MSeedSeries A

    Amplify invests in technical founders building the next generation of applications, models, tools, and infrastructure. For almost 15 years they have…

    2 partners listed
  4. Pillar VC
    $500K–$5MSeedSeries A

    Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming…

    Partners not yet listed
  5. Vertex Ventures
    $500K–$10MSeedSeries A

    We are founders and operators who partner with early-stage founders building infrastructure and SaaS companies, leveraging our experience to help…

    6 partners listed
  6. Sequoia Capital
    $500K–$50MSeedSeries ASeries BSeries CGrowth

    Help the daring build legendary companies through capital, expertise, and network.

    18 partners listed
  7. Mayfield Fund
    SeedSeries A

    First institutional investor for early-stage AI founders, with 70% of investments beginning at inception. People-first approach to building…

    Partners not yet listed
  8. Greylock Partners
    SeedPre-SeedSeries A

    First-check investor (pre-seed, seed, series A) deeply focused on AI-first companies. Partners selectively, cares deeply, and strives for excellence…

    Partners not yet listed

How this list is built

DryPowder lists every fund with a public profile tagged Series A and Infrastructure and headquartered in San Francisco. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 6 funds that publish one.

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Frequently asked questions

How many Series A Infrastructure VCs in San Francisco are there?

As of September 21, 2026, DryPowder lists 8 Series A Infrastructure venture funds in San Francisco with a public profile. The first 5 on this page are True Ventures, BOLDstart Ventures, Amplify Partners, Pillar VC and Vertex Ventures.

Which Series A Infrastructure VCs in San Francisco are actively investing right now?

None of the 8 filed a verified SEC Form D in the last 90 days. A Form D is filed when a fund starts raising; SPVs and single-deal vehicles are not counted.

What check size do Series A Infrastructure VCs in San Francisco write?

The median published range is $500K–$5M, across the 6 of 8 funds that publish a check size. Published checks on this list run from $250K to $50M.

How does DryPowder build this list?

A fund is listed when its public profile is tagged Series A and Infrastructure and its headquarters is San Francisco. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of September 21, 2026.

Sources

Updated