Investor listUpdated October 16, 2026

49 Seed AI & Machine Learning investors in San Francisco

As of October 16, 2026, DryPowder lists 49 seed AI & Machine Learning venture funds in San Francisco. Their median published check range is $250K–$2M (34 of 49 funds publish one). None has filed a verified SEC Form D in the last 90 days.

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Which Seed AI & Machine Learning funds in San Francisco are writing checks right now?

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funds listed: 49
median check (34 of 49 publish one): $250K–$2M
filed an SEC Form D in the last 90 days: 0
last updated, 2026: Oct 16

All 49 Seed AI & Machine Learning funds in San Francisco

Y Combinator
$500K–$2MSeedPre-Seed
YC turns builders into formidable founders by providing structured mentorship, funding, and network access during a 12-week batch program. The…
1 partner listed
Caffeinated Capital
$500K–$5MSeedSeries ASeries BSeries C
Caffeinated offers founders pursuing their life's work an alternative to the hype cycle through long-term thinking, supporting category-defining…
2 partners listed
Boost VC
$500KSeedPre-Seed
Invest first in founders making mutants a reality by reimagining the universe. Generalist investors backing companies that make 1 billion lives…
8 partners listed
Bee Partners
$300K–$500KSeedPre-Seed
Bee Partners backs radical technical founders at inception (pre-product, pre-revenue) with conviction-first capital. They invest in AI supercycle…
1 partner listed
South Park Commons
$250K–$1MSeedPre-Seed
South Park Commons helps talented technologists and founders turn 'illegible into the inevitable' by providing a home for figuring out what's next,…
2 partners listed
Basecase Capital
$1M–$5MSeedPre-Seed
Write the first check to builders who are still dreaming, tinkering, and exploring what they want to create. Work with founders pre-product,…
1 partner listed
AngelPad
$100K–$250KSeed
Seed-stage accelerator focusing on intensive 3-month programs with small cohorts (15 companies per cycle) to help founders achieve product-market…
2 partners listed
Operator Collective
$250K–$2.5MSeedSeries A
Operator Collective is an early-stage B2B venture firm that connects founders to exceptional enterprise operators, believing companies succeed…
20 partners listed
Uncork Capital
$250K–$2MSeed
Uncork invests early in founder potential and AI-native companies creating leverage and unlocking scale before conviction is obvious.
7 partners listed
True Ventures
$250K–$2MSeedSeries A
Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check…
4 partners listed
BOLDstart Ventures
$250K–$5MSeedSeries A
Partner with bold technical founders from inception, before product or first check, backing AI-native infrastructure, security, apps, and models to…
1 partner listed
Primary Venture Partners
$250K–$2MSeed
We back founders building things the world hasn't seen yet, at the moment before the world believes. We are a specialized and scaled seed fund…
9 partners listed
Amplify Partners
$500K–$3MSeedSeries A
Amplify invests in technical founders building the next generation of applications, models, tools, and infrastructure. For almost 15 years they have…
2 partners listed
Treble Capital
$50K–$500KSeed
Support audacious entrepreneurs building consumer technology that transforms how billions experience the world through connectivity, convenience,…
1 partner listed
NFX
$250K–$2MSeedSeries A
NFX identifies and backs founders building companies with network effects. The fund emphasizes software development, founder support through…
6 partners listed
Haystack
$25K–$500KSeed
Backing outlier founders at the earliest stages.
3 partners listed
Neo
$40K–$750KSeedPre-Seed
Neo invests in people and the next generation of founders through pre-seed/seed funding, a startup residency program, and a diverse mentorship…
Partners not yet listed
Inception Studio Capital
$100K–$1.5MSeedPre-Seed
Experienced founders (particularly serial/exit founders) win 22x more often. Zero-equity retreats attract elite repeat founders who avoid traditional…
Partners not yet listed
Pear VC
$250K–$2MSeedPre-Seed
Specialists in pre-seed and seed investing, founded by operators who have built and scaled companies. Provide hands-on support through recruiting,…
Partners not yet listed
Unusual Ventures
$500K–$4MSeedSeries A
The product-market fit partner for technical enterprise founders, turning product-market fit from improbable to inevitable through proprietary…
Partners not yet listed
Weekend Fund
$200K–$500KSeed
Early-stage consumer and B2B investing with founder-led support through product, community building, and GTM alongside an LP collective of 400+…
Partners not yet listed
Scribble Ventures
$750K–$1.5MSeedPre-Seed
Back the world's best AI native founders at pre-seed and seed stages with product and go-to-market expertise from OpenAI, Meta, Twitter, and a16z to…
Partners not yet listed
Founder Collective
$25K–$500KSeedPre-Seed
We're aligned with founders for the long haul, investing at the earliest stages with sector-agnostic conviction in exceptional entrepreneurs. We…
4 partners listed
Eniac Ventures
$250K–$2MSeed
Lead seed rounds and partner with founders from 0 to 1
Partners not yet listed
Air Street
$250K–$2MSeed
Air Street Capital invests in AI-first companies as early as possible, iterating through product, market and technology strategy from day 1 to create…
3 partners listed
Pillar VC
$500K–$5MSeedSeries A
Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming…
Partners not yet listed
Kindred Ventures
$500K–$5MSeedSeries A
Back visionary and relentless founders building the future using technology and science. Belief in AGI for good, decentralized systems, personalized…
Partners not yet listed
Zetta Venture Partners
$500K–$5MSeedSeries A
First believers in AI Native founders, providing zero to one capital and hands-on support for builders of AI Native applications, infrastructure, and…
Partners not yet listed
Day One Ventures
$100K–$5MSeed
Help mission-driven pioneers win by harnessing storytelling, art and culture. Back early-stage companies with customer obsession in their DNA and…
Partners not yet listed
Sequoia Capital
$500K–$50MSeedSeries ASeries BSeries CGrowth
Help the daring build legendary companies through capital, expertise, and network.
18 partners listed
Footwork
$1M–$15MSeedSeries A
Lead and co-lead Series A and Seed rounds in companies with early signs of product-market fit, focusing on consumer technology and consumerization of…
2 partners listed
Argon Ventures
SeedPre-Seed
Pre-seed venture fund leading investments in Intelligent Industry Solutions, focused on AI-led innovation that delivers radical productivity,…
2 partners listed
Baukunst
SeedPre-Seed
Baukunst is a collective of creative technologists advancing the art of building, dedicated to leading pre-seed investments in companies at the…
1 partner listed
Khosla Ventures (Seed)
$500K–$50MSeedGrowth
Bold, early, impactful ventures with brutal honesty. Believe in world-class teams making contrarian bets on impossibly big ideas, from AI to…
1 partner listed
Atomic
Seed
Atomic functions as a co-founder replacement, providing serial entrepreneurs, specialist teams, and resources to de-risk company building and…
2 partners listed
Storm Ventures
$500K–$10MSeedSeries ASeries B
Early stage B2B-focused venture firm specializing in building enterprise leaders through disruptive B2B AI software investments in enterprise…
7 partners listed
Canaan Partners
Seed
Canaan invests in visionaries with transformative ideas where science and technology become society. The firm focuses on early-stage companies that…
Partners not yet listed
Alchemist Accelerator
SeedPre-Seed
Alchemist guides technical founders from possibility to traction through expert coaching, global networks, and direct access to Silicon Valley's…
Partners not yet listed
AgFunder
SeedSeries ASeries B
Investing in deeptech and foundational technologies that remove structural constraints to sustainable scale in food, agriculture, and planetary…
Partners not yet listed
Greylock Partners
SeedPre-SeedSeries A
First-check investor (pre-seed, seed, series A) deeply focused on AI-first companies. Partners selectively, cares deeply, and strives for excellence…
Partners not yet listed
Paradigm
Seed
Paradigm builds and invests across crypto, AI, robotics, and other new frontiers, with a focus on advancing the frontier for everyone through…
Partners not yet listed
Bessemer Venture Partners (Seed)
SeedGrowth
Back audacious founders through dedicated early and growth practices with founder-focused, long-term support across multiple sectors where AI is…
Partners not yet listed
Maven Ventures
SeedSeries ASeries B
Invest in technical founders building software that will improve millions of consumers' lives. Back bold founders with a vision worth fighting for.
Partners not yet listed
Mayfield Fund
SeedSeries A
First institutional investor for early-stage AI founders, with 70% of investments beginning at inception. People-first approach to building…
Partners not yet listed
First Round Capital
$500K–$15MSeed
First Round partners with unreasonable founders at the earliest stages to help them imagine and build transformative companies. The fund focuses on…
Partners not yet listed
Design Fund
Seed
Designer Fund invests in early stage tech companies that use design to improve health, sustainability, or prosperity for all people.
Partners not yet listed
A Capital
SeedGrowth
Providing resources and counsel to forward-thinking companies revolutionizing how we live, work, and play, with favorable terms and less dilution…
Partners not yet listed
Air Street Capital
Seed
Air Street Capital invests in AI-first companies as early as possible, iterating through product, market and technology strategy from day 1 to create…
Partners not yet listed
Piva Capital
SeedSeries ASeries B
Piva Capital invests in people, companies, and breakthrough technologies at the inflection of scientific breakthrough and mass market impact to usher…
Partners not yet listed

How this list is built

DryPowder lists every fund with a public profile tagged Seed and AI & Machine Learning and headquartered in San Francisco. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 34 funds that publish one.

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Frequently asked questions

How many Seed AI & Machine Learning VCs in San Francisco are there?

As of October 16, 2026, DryPowder lists 49 seed AI & Machine Learning venture funds in San Francisco with a public profile. The first 5 on this page are Y Combinator, Caffeinated Capital, Boost VC, Bee Partners and South Park Commons.

Which Seed AI & Machine Learning VCs in San Francisco are actively investing right now?

None of the 49 filed a verified SEC Form D in the last 90 days. A Form D is filed when a fund starts raising; SPVs and single-deal vehicles are not counted.

What check size do Seed AI & Machine Learning VCs in San Francisco write?

The median published range is $250K–$2M, across the 34 of 49 funds that publish a check size. Published checks on this list run from $25K to $50M.

How does DryPowder build this list?

A fund is listed when its public profile is tagged Seed and AI & Machine Learning and its headquarters is San Francisco. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of October 16, 2026.

Sources

Updated October 16, 2026