645 Ventures
Seed to Growth venture capital firm · New York and San Francisco
645 Ventures is a Seed to Growth venture capital firm based in New York and San Francisco that typically writes $1M–$15M checks in Enterprise, Deep Tech and AI Dev Tools. DryPowder has no SEC Form D on file for 645 Ventures as of October 13, 2026.
Updated · Sources: fund website, press
- Typical check
- $1M–$15M
- Stages
- Seed–Growth
- Headquarters
- New York and San Francisco
Overview
645 Ventures at a glance
- Stage
- Seed, Series A, Growth
- Check size
- $1M–$15M
- Sectors
- Enterprise, Deep Tech, AI Dev Tools, Fintech, Consumer, Cybersecurity, Health Tech
- Headquarters
- New York and San Francisco
- Cold inbound
- Accepted
- Website
- 645ventures.com
Investment thesis
645 Ventures invests in exceptional founders with purity of motivation, earned secrets, and non-consensus thinking who defy convention to change the future. They partner with relentless founders across seven domain areas: Enterprise, Deep Tech, AI Infra/DevTools, Fintech, Consumer, Cybersecurity, and Health Tech.
Stated on 645ventures.comWEBSITE
What sets 645 Ventures apart
- Four founder paradigms framework (purity of motivation, earned secrets, obsessed problem solver, non-consensus thinking)
- Deep domain expertise across seven specific sectors
- Hands-on support beyond capital (customer acquisition, go-to-market, fundraising, government relations)
- Focus on pre-product/pre-revenue stage founders
What the portfolio shows
Portfolio 10
Backed: Goldbelly, FiscalNote, Shift5 + 7 more
Partners
Partners at 645 Ventures
Team data is not yet available for 645 Ventures. Visit the website
Activity
Deployment evidence
SEC Form D filings
DryPowder has no SEC Form D on file for 645 Ventures in the last three years.
In the news
See all in deal flowSimilar funds
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FAQ
Questions about 645 Ventures
What does 645 Ventures invest in?
645 Ventures is a Seed, Series A, Growth stage Enterprise, Deep tech, Ai devtools, Fintech, Consumer, Cybersecurity, Health tech investor, typically writing $1M – $15M checks, primarily investing in US. Their thesis: 645 Ventures invests in exceptional founders with purity of motivation, earned secrets, and non-consensus thinking who defy convention to change the future. They partner with relentless founders across seven domain areas: Enterprise, Deep Tech, AI Infra/DevTools, Fintech, Consumer, Cybersecurity,…
What check size does 645 Ventures write?
645 Ventures typically writes $1M – $15M checks at the Seed, Series A, Growth stage in Enterprise, Deep tech, Ai devtools, Fintech, Consumer, Cybersecurity, Health tech.
What makes 645 Ventures different from other funds?
645 Ventures stands out on 4 points: Four founder paradigms framework (purity of motivation, earned secrets, obsessed problem solver, non-consensus thinking); Deep domain expertise across seven specific sectors; Hands-on support beyond capital (customer acquisition, go-to-market, fundraising, government relations); Focus on pre-product/pre-revenue stage founders.
What other funds are similar to 645 Ventures?
Funds with an overlapping stage and sector focus include Caffeinated Capital, SignalFire, Greylock Partners.
How do I reach 645 Ventures?
645 Ventures accepts cold inbound, so a warm introduction is not required. 645 Ventures publishes an application route at https://airtable.com/appGb8jJGlicUkjgn/pagSRwwW1RXpwNtZr/form.
Sources
- Website: 645 Ventures website (645ventures.com)
- Press: news.crunchbase.com article mentioning 645 Ventures,
- Method: How DryPowder builds its data
Updated