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19 Seed Infrastructure investors in San Francisco

As of October 4, 2026, DryPowder lists 19 seed Infrastructure venture funds in San Francisco. Their median published check range is $500K–$3M (15 of 19 funds publish one). None has filed a verified SEC Form D in the last 90 days.

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funds listed
19
median check (15 of 19 publish one)
$500K–$3M
filed an SEC Form D in the last 90 days
0
last updated, 2026
Oct 4

All 19 Seed Infrastructure funds in San Francisco

  1. $500K–$2MSeedPre-Seed

    YC turns builders into formidable founders by providing structured mentorship, funding, and network access during a 12-week batch program. The…

    1 partner listed
  2. $250K–$1MSeedPre-Seed

    South Park Commons helps talented technologists and founders turn 'illegible into the inevitable' by providing a home for figuring out what's next,…

    2 partners listed
  3. $1M–$5MSeedPre-Seed

    Write the first check to builders who are still dreaming, tinkering, and exploring what they want to create. Work with founders pre-product,…

    1 partner listed
  4. $250K–$2MSeed

    Uncork invests early in founder potential and AI-native companies creating leverage and unlocking scale before conviction is obvious.

    7 partners listed
  5. $250K–$2MSeedSeries A

    Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check…

    4 partners listed
  6. $250K–$5MSeedSeries A

    Partner with bold technical founders from inception, before product or first check, backing AI-native infrastructure, security, apps, and models to…

    1 partner listed
  7. $250K–$5MSeed

    Champion inspired and obsessive builders across seed stage, from enterprise SaaS to sustainability, health, hard tech, AI, infrastructure, consumer,…

    6 partners listed
  8. $250K–$2MSeed

    We back founders building things the world hasn't seen yet, at the moment before the world believes. We are a specialized and scaled seed fund…

    9 partners listed
  9. $500K–$3MSeedSeries A

    Amplify invests in technical founders building the next generation of applications, models, tools, and infrastructure. For almost 15 years they have…

    2 partners listed
  10. $25K–$500KSeed

    Backing outlier founders at the earliest stages.

    3 partners listed
  11. $750K–$1.5MSeedPre-Seed

    Back the world's best AI native founders at pre-seed and seed stages with product and go-to-market expertise from OpenAI, Meta, Twitter, and a16z to…

    Partners not yet listed
  12. $500K–$5MSeedSeries A

    Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming…

    Partners not yet listed
  13. $500K–$10MSeedSeries A

    We are founders and operators who partner with early-stage founders building infrastructure and SaaS companies, leveraging our experience to help…

    6 partners listed
  14. $500K–$50MSeedSeries ASeries BSeries CGrowth

    Help the daring build legendary companies through capital, expertise, and network.

    18 partners listed
  15. SeedPre-SeedSeries A

    First-check investor (pre-seed, seed, series A) deeply focused on AI-first companies. Partners selectively, cares deeply, and strives for excellence…

    Partners not yet listed
  16. SeedGrowth

    Back audacious founders through dedicated early and growth practices with founder-focused, long-term support across multiple sectors where AI is…

    Partners not yet listed
  17. SeedSeries A

    First institutional investor for early-stage AI founders, with 70% of investments beginning at inception. People-first approach to building…

    Partners not yet listed
  18. $500K–$15MSeed

    First Round partners with unreasonable founders at the earliest stages to help them imagine and build transformative companies. The fund focuses on…

    Partners not yet listed
  19. Seed

    Paradigm builds and invests across crypto, AI, robotics, and other new frontiers, with a focus on advancing the frontier for everyone through…

    Partners not yet listed

How this list is built

DryPowder lists every fund with a public profile tagged Seed and Infrastructure and headquartered in San Francisco. Funds whose largest published check is $5M or less come first; inside each group, funds with a verified SEC Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, and SPV and single-deal filings are dropped. Check sizes are what each fund publishes; the median uses only the 15 funds that publish one.

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Frequently asked questions

How many Seed Infrastructure VCs in San Francisco are there?

As of October 4, 2026, DryPowder lists 19 seed Infrastructure venture funds in San Francisco with a public profile. The first 5 on this page are Y Combinator, South Park Commons, Basecase Capital, Uncork Capital and True Ventures.

Which Seed Infrastructure VCs in San Francisco are actively investing right now?

None of the 19 filed a verified SEC Form D in the last 90 days. A Form D is filed when a fund starts raising; SPVs and single-deal vehicles are not counted.

What check size do Seed Infrastructure VCs in San Francisco write?

The median published range is $500K–$3M, across the 15 of 19 funds that publish a check size. Published checks on this list run from $25K to $50M.

How does DryPowder build this list?

A fund is listed when its public profile is tagged Seed and Infrastructure and its headquarters is San Francisco. Funds whose largest published check is $5M or less come first; within each group, funds that filed a Form D in the last 30 days lead, then profile quality decides. Form D dates come from SEC EDGAR, with SPVs excluded. Data as of October 4, 2026.

Sources

Updated