17 Seed Infrastructure Investors in San Francisco — 17 Currently Deploying
Updated
Funds (17)
South Park Commons helps talented technologists and founders turn 'illegible into the inevitable' by providing a home for figuring out what's next, transitioning from -1 to 0 (pre-…
We are founders and operators who partner with early-stage founders building infrastructure and SaaS companies, leveraging our experience to help technical founders nail go-to-mark…
YC turns builders into formidable founders by providing structured mentorship, funding, and network access during a 12-week batch program. The program transforms early-stage teams …
Uncork invests early in founder potential and AI-native companies creating leverage and unlocking scale before conviction is obvious.
Write the first check to builders who are still dreaming, tinkering, and exploring what they want to create. Work with founders pre-product, pre-traction, and often pre-idea.
Accelerating AI-native founders at the earliest stages. Lead early rounds in companies and founders building the future, providing that first check before others think you're onto …
Partner with bold technical founders from inception, before product or first check, backing AI-native infrastructure, security, apps, and models to build the autonomous enterprise.
Champion inspired and obsessive builders across seed stage, from enterprise SaaS to sustainability, health, hard tech, AI, infrastructure, consumer, and crypto. Provide guidance fr…
Amplify invests in technical founders building the next generation of applications, models, tools, and infrastructure. For almost 15 years they have been the first investor and par…
We back founders building things the world hasn't seen yet, at the moment before the world believes. We are a specialized and scaled seed fund designed to actually deliver with dee…
Back the world's best AI native founders at pre-seed and seed stages with product and go-to-market expertise from OpenAI, Meta, Twitter, and a16z to help them reshape the world.
Partner at inception with technically brilliant founders who see past impossible to inevitable. Invest in technical breakthroughs becoming world-changing companies, particularly in…
First-check investor (pre-seed, seed, series A) deeply focused on AI-first companies. Partners selectively, cares deeply, and strives for excellence in reshaping industries through…
First institutional investor for early-stage AI founders, with 70% of investments beginning at inception. People-first approach to building breakthrough companies.
Paradigm builds and invests across crypto, AI, robotics, and other new frontiers, with a focus on advancing the frontier for everyone through software development and open source c…
First Round partners with unreasonable founders at the earliest stages to help them imagine and build transformative companies. The fund focuses on being the world's best partner f…
Which of these Seed Infrastructure funds actually fits your startup?
DryPowder's AI matching ranks all 17 by thesis fit, check size, and deployment status.
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Frequently asked questions
How many seed infrastructure investors are actively deploying right now?
DryPowder tracks 17 seed infrastructure funds. Of these, 17 are currently deploying capital based on recent fund closes, portfolio activity, and partner signals. Use DryPowder's fund matching to see which ones fit your specific startup.
What check size do seed infrastructure VCs write?
Among 17 seed infrastructure funds on DryPowder, check sizes run from $25K–$15M. Ranges vary by fund size, vintage, and whether the fund leads rounds. Each fund profile shows check size detail and lead preference.
How do I get a meeting with a seed infrastructure VC?
A warm intro is still the fastest path. Most seed infrastructure VCs on DryPowder do accept cold outreach or direct applications, but response rates vary widely by fund. Before reaching out, use DryPowder's AI matching to get a fit score and specific talking points. Founders who lead with thesis-aligned framing get significantly better response rates than those sending the same deck to every fund on a list.
How long does a seed round typically take to close?
Seed rounds typically take 3-6 months from first meeting to close. Most of that time is spent on qualification: investors want to see early traction, run multiple meetings, and often complete reference checks. With a committed lead who sets terms, the rest of the round usually fills within 2-4 weeks. Without a lead, the process drags. DryPowder's deployment signals help identify which seed funds are actively writing checks right now versus sitting between vehicles.
How many seed infrastructure investors should I be talking to at once?
Most fundraisers recommend a parallel process: identify 20-40 target investors but approach your highest-fit funds first. Of the 17 seed infrastructure funds currently deploying, not all will match your specific stage and sector. Use fund matching to find your top 10-15, approach those first, collect feedback, then go wider. Going to every fund simultaneously without qualifying first burns bridges and dilutes the urgency that helps close a round.
How is DryPowder different from building a VC list on LinkedIn or Crunchbase?
The fund list you build on LinkedIn or Crunchbase is roughly the same list every other founder is building. DryPowder adds three things a manual search cannot: deployment signals (which funds have recently closed new vehicles and are actively writing checks), AI thesis matching (which of the 17 seed infrastructure funds actually fits your specific startup, ranked by fit), and verified partner contact details. The goal is 15 targeted, thesis-aligned pitches instead of 150 generic ones.
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